Mabwell Therapeutics is a growing biotech company focused on developing antibody-based innovative therapeutics for rare and debilitating diseases. We are looking for a highly motivated, independent and goal-oriented research scientist to join our small and yet efficient and dedicated team. The ideal candidate will have a strong background in immunology, with a proven track record of designing and executing experiments to support drug discovery and development.

The candidate will actively participate in scientific and technical innovations in the company, engage in target identification and validation processes, and be responsible for developing and performing biochemical and cell-based assays to enable Mabwell drug discovery programs. In addition, the candidate will contribute to the design/execution of in vivo studies to investigate the mechanism of action and to characterize PK/PD/efficacy of drug candidates.

DUTIES AND RESPONSIBILITIES:

• Design, plan and execute studies and experiments with minimum supervision
• Develop and conduct cell-based functional assays to characterize drug candidates using assays such as reporter assays, ELISA, flow cytometry, and RT-qPCR
• Design and conduct in vitro and in vivo experiments to evaluate the efficacy and mechanism of action of Mabwell drug candidates
• Develop and validate bioanalytical assays for PK and biomarker analyses
• Analyze and interpret experimental data, and communicate results at team meetings
• Drive discussions to actionable next steps
• Work with external collaborations, including academic institutions and CROs to achieve project goals and timeline
• Stay current with literature and scientific advances in the field related to company projects and specific disease areas
• Writes and reviews manuscripts for publication, and presents at scientific meetings
• Other duties as needed for project advancement

KNOWLEDGE/SKILLS/ABILITIES REQUIRED:

• PhD in Immunology, Cell Biology, or related field with 2+ years of industry or postdoctoral experience; MS with minimum 4 years of experience in pharma/biotech environment
• Extensive hands-on experience with cell and molecular biology, protein biochemistry, and their applications in bioassay development and drug discovery
• Experienced in mouse handling, dosing and blood/tissue collection
• Ability to multi-task/ prioritize and time management of daily activities
• Ability to work indepedentely and as a team player in a fast-paced team environment, meet deadlines and company objectives
• Flexibility with working on novel targets and various disease areas
• Scientific background in immunology is highly desirable
• Experience with different animal models is a plus
• Experience with rare disease indications and orphan drug development is preferred

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. The level and title of this position will be based on the final candidate’s qualificatioins. We are committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, national origin, genetics, disability, age, sexual orientation or veteran status. We also offer a competitive benefits package for our employees and their families, which includes 401(k), medical, dental, and vision insurances. If you are a self-starter, with a passion for science and a desire to make a difference in patients’ lives, we encourage you to apply for this exciting opportunity. To apply, please submit your CV and cover letter to info@mabwell-therapeutics.com.